Object - Process Modeling of Glucose Metabolism in Health and Disease

Object-oriented design and layered hierarchical architecture are the dominant paradigms for building computerbased applications. The biological system has significant nonoverlap with these paradigms. This poses challenges in integrating seamlessly computer and biological systems. A seamless system could help build personalized patient monitoring/management systems for chronic conditions such as Diabetes. We take the first step in that direction by depicting glucose metabolism using object-oriented design and hierarchy. It is shown that the hierarchy principle will require creation of virtual objects. Resulting data coherence and consistency issues are addressable, as with cache coherency algorithms in the computer domain.